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Dr. Manuel Liebeke

Group leader

MPI for Marine Microbiology
Celsiusstr. 1
D-28359 Bremen




+49 421 2028-8220

Dr. Manuel Liebeke

My Main Research Interests

The research in my group focuses on the chemical interactions between bacterial symbionts and their eukaryotic hosts. I am convinced Mass Spectrometry based Metabolomics can provide us with a detailed view into the metabolic interactions.
My group develops high-resolution Spatial Imaging Methods for in situ measurements of metabolites in host-microbe systems named 
spatial metabolomics. 

Research projects

Our major approaches are:

  • spatial metabolomics on host-microbe systems 
  • Mass spectrometry Imaging on the µm scale
  • correlative imaging approaches,
    • e.g. combining MALDI-MSI with FISH to map bacteria
    • 3D scanning approaches like µCT to get 3D anatomy of hosts
  • environmental metabolomics
    • marine metabolomics, measure metabolites in seawater
    • tissue extracts of animals, plants and microorganisms directly sampled in the field
    • sediment porewater metabolites
  • stable isotope tracer experiments
    • following the fate of 13C or deuterated metabolites in symbiotic systems with MS
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