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Research Group Metabolic Interactions

We use modern mass-spectrometry methods to understand which molecules are involved in marine host-microbe systems, how different metabolites shape ecological communities, and how the symbiotic partners respond metabolically to environmental changes.

The research in this lab is constantly driven by method developments like high-resolution mass-spectrometry imaging to reveal the spatial metabolome of microbial systems. Our expertise is microbial metabolomics with a special focus on marine systems.

Group leader

Dr. Manuel Liebeke

MPI for Marine Microbiology
Celsiusstr. 1
D-28359 Bremen




+49 421 2028-8220

Dr. Manuel Liebeke
Research Group Metabolic Interactions 2021
Research Group Metabolic Interactions 2021

Latest News

Showing 1-5 of 15 items.

We welcome our new intern, Tomasz Markowski

Feb 1, 2022

Hi my name is Tomasz and I will be working as laboratory assistant in MS-group in Symbiosis department. An internship in the institute is part of my studies: Chemical and Biotechnical Science at the Business Academy Aarhus. I have always enjoyed working in a field of chemistry and this is the rea...

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We welcome our new Post Doc, Jana Geuer:

Jan 17, 2022

Hello everyone!

My name is Jana and I will be working on the sea4soCiety project to better understand the role of metabolites in carbon sequestration within coastal environments. Previously, my research focused on the interaction between organic matter and metals in aquatic systems. I am particu...

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Grace D'Angelo presented her poster at ASMS

Nov 3, 2021

Grace D'Angelo presented her poster entitled, 'Exploring Carbon Cycling in Complex Microbial Communities with Metaproteome-derived Stable Isotope Fingerprints' at the American Society for Mass Spectrometry (ASMS) conference. This project and poster are part of collaborative work with the Kleiner ...

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Sea4Society Project is Underway

Aug 27, 2021

De­vel­op­ing in­nov­at­ive and so­cially ac­cep­ted ap­proaches to im­prove the nat­ural po­ten­tial for car­bon stor­age in ve­get­a­tion-rich coastal eco­sys­tems: that is the goal of the new re­search con­sor­tiumsea4soCiety, in which the Max Planck In­sti­tute for Mar­ine Mi­cro­bi­o­logy in...

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Select Publications

Michellod, D., Bien, T., Birgel, D., Jensen, M., Kleiner, M., Fearn, S., Zeidler, C., Gruber-Vodicka, H. R., Dubilier, N., Liebeke, M. 2022. "De novo phytosterol synthesis in animals" bioRxiv; doi:
Geier BOetjen JRuth Steiner BPolikarpov M, Gruber-Vodicka HR, Liebeke M2021. Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography. PNAS. 118 (27) e2023773118; 10.1073 / pnas.2023773118
Janda M, Seah BKB, Jakob D, Beckmann J, Geier B, and Liebeke M. 2021. Determination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets. Analytical Chemistry. 93 (24): 8399-8407. 10.1021 / acs.analchem.0c04720 
Geier, B., Sogin, E., Michellod, D., Janda, M., Kompauer, M., Spengler, B., Dubilier, N. & Liebeke M. 2020. Spatial metabolomics of in situ host - microbe interactions at the micrometer scale. Nature Microbiology.
Sogin EM, Puskás E, Dubilier N, Liebeke M. 2019. Marine Metabolomics: a method for nontargeted measurement of metabolites in seawater by gas chromatography - mass spectrometry. mSystems 4 (6): e00638-19. 10.1128 / mSystems.00638-19


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